By Chris Michiels, Douglas H. Bartlett, Abram Aertsen
* First quantity solely dedicated to the consequences of excessive strain on microorganisms * Brings jointly the high-pressure body structure of piezophiles and non-piezophiles * Spans the diversity from easy technology to sensible functions * presents primary perception for nutrition technologists utilizing excessive strain for foodstuff renovation * contains special fabric to demonstrate bacterial variations to severe high-pressure environments * presents a foundation for novel biotechnological functions utilizing excessive strain * Highlights the microbial wealth and ecological effect of the deep biosphere * accomplished resource of data on ecology, body structure, and genomics of deep sea micro organism
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* First quantity fullyyt dedicated to the consequences of excessive strain on microorganisms * Brings jointly the high-pressure body structure of piezophiles and non-piezophiles * Spans the diversity from simple technology to useful functions * offers basic perception for nutrition technologists using excessive strain for nutrition renovation * contains exact fabric to demonstrate bacterial variations to severe high-pressure environments * presents a foundation for novel biotechnological purposes utilizing excessive strain * Highlights the microbial wealth and ecological effect of the deep biosphere * finished resource of knowledge on ecology, body structure, and genomics of deep sea micro organism
The examine of the genetic legislation of immune reaction to ordinary multidetermi nant immunogens was once undertaken via the tactic of bidirectional selective breed ing of excessive or Low antibody responder traces of mice. 5 decisions are defined: choice I, performed for agglutinin responsiveness to sheep erythrocytes and pigeon erythrocytes alternated in each one new release.
''Informative, well-constructed, and readable. .. The members are leaders of their fields and what they must say is worth it. '' --- SGM Quarterly, August 1998
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Extra info for High-Pressure Microbiology
These maturation events are crucial to make the particle infectious. The mature particles were more unstable against pressure than the cleavage-defective particles (Fig. 3), which can be explained by the metastability elicited upon maturation (28). We also have evidence that the gamma subunit is released after a cycle of compression and decompression. A similar situation would occur with picornaviruses, with pressure-induced release of VP4 (Fig. 2). In both cases, pressure induces the formation of a noninfectious particle, apparently a fusion-active state of these nonenveloped viruses.
Johnson, and J. L. Silva. 1994. Differences in pressure stability of the three components of cowpea mosaic virus: implications for virus assembly and disassembly. Biochemistry 33:8339– 8346. 9. Da Poian, A. , A. C. Oliveira, and J. L. Silva. 1995. Cold denaturation of an icosahedral virus. The role of entropy in virus assembly. Biochemistry 34:2672–2677. 10. De Souza, P. , R. Tuma, P. E. Prevelige, J. L. Silva, and D. Foguel. 1999. Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation.
FHV is an RNA insect virus; it is nonenveloped and a member of the family Nodaviridae. It is composed of a bipartite single-stranded RNA genome packaged in an icosahedral capsid of 180 copies of an identical protein (alpha protein). A fundamental property of many animal viruses is the postassembly maturation required for infectivity. FHV is constructed as a provirion, which matures to an infectious virion by cleavage of alpha protein into beta and gamma subunits. We found that maturation cleavage leads into a metastable state, in which dissociation of the coat protein is coupled to unfolding.
High-Pressure Microbiology by Chris Michiels, Douglas H. Bartlett, Abram Aertsen